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【目的】探索胚胎停止发育的环境危险因素,为胎儿的健康发育提供预防策略。【方法】采用医院为基础的病例对照方法,自制调查表对来院就诊确定为胚胎停止发育的病例128例和胚胎发育正常者257例为对照进行问卷调查,运用单因素和多因素非条件logistic回归分析。【结果】单因素分析发现胚胎停止发育与职业,工作环境中的噪声、振动、粉尘、电离辐射以及生活习惯和家庭环境中的偏食、孕期熬夜、烫染发、孕前服用避孕药、饮茶、饮酒、吸烟、住房装修等有关;多因素分析显示:孕期熬夜(OR=2.672)、吸烟习惯(OR=2.672)、住房装修(OR=2.605)、孕期看电视或电脑(OR=7.482)是主要影响因素。【结论】胚胎停止发育由多因素作用导致,个人生活习惯和家庭环境起重要作用。
【Objective】 Explore the environmental risk factors of embryo stop development and provide preventive strategies for the healthy development of fetus. 【Methods】 A hospital-based case-control method and a self-made questionnaire were used to survey 128 cases of stopped embryos and 257 cases of normal embryos as controls. analysis. 【Result】 Univariate analysis showed that embryos stop developing and occupational, work environment noise, vibration, dust, ionizing radiation and partial eclipse in living habit and family environment. Pregnancy stay up late, hot hair, preconception contraceptives, drinking tea, drinking (OR = 2.672), housing decoration (OR = 2.605), watching TV or computer during pregnancy (OR = 7.482) were the main influence factor. 【Conclusion】 The development of embryo stops due to many factors, and personal habits and family environment play an important role.