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目的:探讨中老年高血压患者服药情况及对血压曲线影响,为中老年高血压患者的治疗提供依据。方法:选取2012年12月-2014年12月门诊及住院收治的中老年高血压患者800例进行研究,询问患者病史和所服药物,并对其服用现有降压药物的情况进行24h动态血压监测,观察用药对血压曲线的影响。结果:800例高血压患者单药治疗有319例,占39.88%,其中短效药物有211例,占66.14%,中长效药物有108例,占33.86%;联合用药有481例,占60.12%,其中短效联合有301例,占62.58%,中长效联合有180例,占37.42%;经24h动态血压曲线研究发现,无论是单药治疗还是联合治疗,中长效其杓型、非杓型、超杓型、清晨高血压比例与短效联合药物比较,差异均有统计学意义,P<0.05。结论:中老年高血压患者最好采取联合降压的治疗方式,并采用中长效药物,以有效、平稳降压。
Objective: To investigate the medication in middle-aged and elderly hypertensive patients and the impact of blood pressure curve, provide the basis for the treatment of middle-aged and elderly hypertensive patients. Methods: From December 2012 to December 2014, 800 outpatients and hospitalized patients with middle-aged and elderly patients with hypertension were enrolled in this study. Patients’ medical history and medication were taken and their ambulatory blood pressure Monitor, observe the effect of medication on blood pressure curve. Results: There were 319 cases (39.88%) with monotherapy in 800 hypertensive patients, of which 211 cases were short-acting drugs, accounting for 66.14%; 108 cases were medium-to-long-acting drugs, accounting for 33.86%; 481 cases were combined with drugs, accounting for 60.12%. %, Including short-acting combination of 301 cases, accounting for 62.58%, mid-long-term combination of 180 cases, accounting for 37.42%; 24h by the dynamic blood pressure curve found that either monotherapy or combination therapy, Non-dipper type, super dipper type, early morning hypertension ratio and short-acting combination of drugs, the difference was statistically significant, P <0.05. Conclusion: It is best to take combined antihypertensive treatment in middle-aged and elderly hypertensive patients, and use medium and long-acting drugs to effectively and steadily decrease blood pressure.