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目的探讨小剂量地塞米松对新生儿胎粪吸入性肺炎细胞因子的影响。方法整理40例新生儿胎粪吸入性肺炎患者,在治疗过程中分为治疗组和对照组,两组患者均使用综合治疗,其中治疗组患者在治疗过程中联合小剂量地塞米松进行治疗,观察两组患者的临床治疗效果。结果治疗组患者的临床治疗时间比对照组短,同时患者在临床检测过程中,其白介素-6、白介素-8、肿瘤坏死因子TNF-a明显低于对照组患者,临床治疗效果显著。结论在临床新生儿胎粪吸入性肺炎患者的治疗过程中,联合小剂量地塞米松治疗,可以有效的提高患者的临床治疗效果,对患者的细胞因子治疗方面效果也较好,在临床治疗当中可以选择使用,提高患者的临床治疗效果。
Objective To investigate the effect of low dose dexamethasone on cytokines in neonates with meconium aspiration pneumonia. Methods A total of 40 neonates with meconium aspiration pneumonia were collected and divided into treatment group and control group. The two groups of patients were treated with combination therapy. The treatment group was treated with low-dose dexamethasone, The clinical effects of two groups were observed. Results The clinical treatment time of the treatment group was shorter than that of the control group. At the same time, the levels of IL-6, IL-8 and tumor necrosis factor-α in the treatment group were significantly lower than those in the control group. The clinical effect was significant. Conclusion In the course of treatment of patients with clinical meconium aspiration pneumonia, the combination of low-dose dexamethasone can effectively improve the clinical effect of treatment and the effect of cytokines in patients is also good. In clinical treatment Can choose to use to improve the patient’s clinical treatment.