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目的了解河源市城区出生缺陷发生率,探讨出生缺陷发生的相关因素。方法对2004年1月-2007年12月市城区住院分娩的围产儿进行监测。结果出生缺陷发生率为16.69‰,出生缺陷儿死亡率为459.18‰;农村出生缺陷发生率显著高于城镇(P<0.01);双胎出生缺陷发生率高于单胎(P<0.01);第一季度的出生缺陷发生率明显高于第四季度(P<0.05)。结论普及优生优育知识,加强婚前保健及孕前、孕期保健和产前诊断工作,继续开展出生缺陷监测工作的病因学研究。
Objective To understand the incidence of birth defects in urban areas of Heyuan City and explore the related factors of birth defects. Methods From January 2004 to December 2007, the perinatal delivery in hospital in urban area was monitored. Results The incidence of birth defects was 16.69 ‰, and the birth defect mortality rate was 459.18 ‰. The incidence of birth defects in rural areas was significantly higher than that in urban areas (P <0.01). The incidence of birth defects was higher than that of single births (P <0.01) The incidence of birth defects in the first quarter was significantly higher than in the fourth quarter (P <0.05). Conclusions Popularizing the knowledge of prenatal and postnatal care, strengthening premarital health and prenatal care and prenatal diagnosis, and continuing to carry out the etiology of birth defects monitoring.