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目的：探讨兰索拉唑治疗十二指肠溃疡的临床疗效。方法我院收治十二指肠溃疡患者68例，分为观察组和对照组。两组患者均采用常规治疗，在此基础上，观察组加用兰索拉唑，对照组加用雷尼替丁，观察两组患者的临床疗效。结果对照组治疗患者的痊愈率为56.25%，总有效率为87.5%；而观察组治疗患者的痊愈率为86.1%，总有效率为100%，明显高于对照组( p0.05)。结论对十二指肠溃疡患者应用兰索拉唑进行治疗，能够有效的增强治疗效果，提高治疗总有效率，值得临床推广。“,”objective to investigate the sora clinical curative effect of treatment of duodenal ulcer. methods Our hospital 68 cases of duodenal ulcer patients, divided into observation group and control group. Two groups of patients were used conventional treatment, on this basis, the observation group added with orchid sola, control group and ranitidine used, to observe the clinical efficacy of two groups of patients. Results the control group in the treatment of patients with recovery rate was 56.25%, total effective rate was 87.5%; To observe the healing rate was 86.1% in the treatment group patients, the total effective rate was 100%, significantly higher than the control group (p0.05). Conclusion application of orchid sora azole treatment in patients with duodenal ulcer, effectively enhance the treatment effect, increase the total effective rate, worthy of clinical promotion.