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目的:探讨儿童严重创伤后的药学监护点、用药注意事项及药师在促进儿童合理用药中的作用。方法:为1例8岁坠落伤患儿制订个体化治疗方案:哌拉西林/他唑巴坦4g,q8h抗感染;口服盐酸曲马多缓释片50mg,q12h,止痛;停用抗菌药物、补充益生菌、维持水和电解质平衡,治疗抗菌药物相关性腹泻,并进行药学监护。结果:临床药师根据小儿用药特点,从抗感染药选择、止痛方案制订、药品不良反应监测等方面作为切入点,对创伤患儿开展药学监护。患儿情况好转,会阴伤口基本愈合,经小儿骨科评估骨折处外固定架情况后出院。结论:临床药师对严重创伤患儿实施药学监护,可优化治疗方案,确保儿童用药的安全、经济、有效。
OBJECTIVE: To investigate the points of care of children after severe trauma, precautions of medication and the role of pharmacists in promoting rational drug use in children. Methods: To develop a personalized treatment plan for 1 patient with 8-year-old fall injury: piperacillin / tazobactam 4g, anti-infection q8h; oral tramadol hydrochloride 50mg, q12h, analgesic; disable antibacterial drugs, Supplement probiotics, maintain water and electrolyte balance, treat antibiotic-associated diarrhea, and administer medical care. Results: Based on the characteristics of pediatric medication, clinical pharmacists started the pharmacy care of infants with traumatic injuries based on the selection of anti-infectives, the formulation of pain relief plans and the monitoring of adverse drug reactions. The condition of children improved, perineal wound basically healed, the pediatric orthopedic fracture external fixator assessment after discharge. Conclusion: Pharmacists take clinical care to children with severe trauma and can optimize the treatment plan to ensure the safe, economical and effective medication for children.