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目的分析肺心病心力衰竭患者心功能与血浆脑钠肽和超敏C反应蛋白的关系。方法选取53例肺心病心力衰竭患者作为研究组;再选取同期检查身体的健康体检者53例作为对照组,2组接受血浆脑钠肽和超敏C反应蛋白检查(24h内)。对比2组及不同心功能患者血浆脑钠肽和超敏C反应蛋白水平。结果研究组血浆脑钠肽和超敏C反应蛋白水平均高于对照组(P<0.05)。研究组患者随着心功能级别升高,血浆脑钠肽和超敏C反应蛋白水平上升,各级间差异有统计学意义(P<0.05)。结论肺心病心力衰竭患者血浆脑钠肽和超敏C反应蛋白水平升高,可用于肺心病心力衰竭的辅助诊断。
Objective To analyze the relationship between cardiac function and plasma brain natriuretic peptide and high-sensitivity C-reactive protein in patients with cor pulmonale heart failure. Methods Fifty-three patients with heart failure of cor pulmonale were selected as the study group. Fifty-three healthy volunteers were enrolled in the study. Plasma BNP and high-sensitivity C-reactive protein were examined in two groups within 24 hours. The levels of plasma brain natriuretic peptide and high-sensitivity C-reactive protein were compared between two groups and patients with different cardiac function. Results The levels of plasma brain natriuretic peptide and high-sensitivity C-reactive protein in the study group were higher than those in the control group (P <0.05). In the study group, the levels of plasma brain natriuretic peptide and high-sensitivity C-reactive protein increased with the increase of cardiac function, and there was a significant difference among all levels (P <0.05). Conclusions Patients with cor pulmonale heart failure patients with elevated plasma levels of brain natriuretic peptide and high-sensitivity C-reactive protein can be used for the diagnosis of heart failure of cor pulmonale.