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目的探讨广西地区复发转移乳腺癌临床病理因素、激素受体状况及二者相关性。方法应用免疫组化方法,检测接受根治手术的女性乳腺癌患者100例中的ER、PR、CerbB-2、表达情况。结果发病年龄、肿瘤大小、腋淋巴结转移状况、pTNM分期、ER的表达与乳腺癌患者根治手术后累积复发转移率有关,多因素分析显示最终进入COX模型的仅有ER。结论乳腺癌术后复发转移与发病年龄、肿瘤大小、腋淋巴结转移状况、pTNM分期有关。ER可作为乳腺癌术后复发转移的预测指标。
Objective To investigate the clinicopathological factors, hormone receptor status and their correlation in recurrent and metastatic breast cancer in Guangxi. Methods Immunohistochemistry was used to detect the expression of ER, PR and CerbB-2 in 100 cases of breast cancer patients undergoing radical operation. Results The age of onset, tumor size, axillary lymph node metastasis, pTNM stage and ER expression were related to the cumulative recurrence and metastasis rate after radical operation in patients with breast cancer. Multivariate analysis showed that only ER was finally entered into the COX model. Conclusion The postoperative recurrence and metastasis of breast cancer is related to the age of onset, tumor size, axillary lymph node metastasis and pTNM stage. ER can be used as a predictor of recurrence and metastasis of breast cancer.