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小檗碱是中药复方前列栓[1] 的有效成分之一 ,本研究应用 RP- HPLC测定小檗碱血清药物浓度 ,对兔一次性肛塞前列栓后小檗碱药动学进行研究 ,为前列栓的临床合理用药提供实验依据。1 材料1 .1 药物与试剂 :前列栓 ,2 g/栓 ,每粒栓剂含小檗碱的最低含量为 34mg,由北京中医药大
Berberine is one of the active ingredients of Chinese herbal medicine compound Qianliexiu [1]. In this study, RP-HPLC was used to determine the concentration of berberine in serum, and the pharmacokinetics of berberine after anterior plug embolization in rabbits was studied. The clinical rational use of the forehead thrombus provides experimental basis. 1 Materials 1.1 Drugs and Reagents: Forefront thrombus, 2 g/plug, each containing suppository with a minimum content of 34 mg, from Beijing University of Traditional Chinese Medicine