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本实验于1982年6月至1884年6月在海南岛东方区医院进行。作者联合使用甲氟喹、法西达和青蒿素治疗当地抗氯喹株的恶性疟患者,并对其疗效及产生的副作用进行了研究。实验所选择的病例均为发热,末稍血涂片每μl含恶性疟原虫无性体1000个(或发热超过5天者,血内原虫含量大于5000个/ul),未经治疗,年龄为8～60岁又无其它明显严重疾病的患者,其中男69例,女21例。实验分为A-D4个治疗组,每组20例。
The experiment was performed in Dongfang District Hospital of Hainan Island from June 1982 to June 1884. The authors used mefloquine, faxidac and artemisinin to treat patients with local resistance to chloroquine resistant strains of falciparum malaria and investigated their efficacy and side effects. The patients selected for the experiment were all feverish. The final blood smear contained 1000 pieces of Plasmodium falciparum asexual (or more than 5 days of fever, blood protozoa more than 5000 / ul), untreated, and an age of 8 ~ 60 years old and no other obvious serious diseases, including 69 males and 21 females. The experiment was divided into A-D4 treatment groups, 20 cases in each group.