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目的探讨围手术期输血对直肠癌术后复发及预后的影响。方法回顾性分析本院1994年6月至2003年6月收治的156例直肠癌Duckes C期根治手术病例输血情况和随访结果,比较输血组与未输血组术后复发情况及预后情况。结果输血组术后复发率较未输血组高(P=0.034),输血量>600ml组比输血量<600ml组复发率高,差异有统计学意义(P=0.037)。输血组与未输血组生存率之间比较差异无统计学意义(P=0.458)。结论输血可增加直肠癌患者术后复发率,缩短术后无瘤生存期,临床用血应仔细权衡。
Objective To investigate the effect of perioperative blood transfusion on postoperative recurrence and prognosis of rectal cancer. Methods We retrospectively analyzed the transfusion status and follow-up results of 156 cases of Duckes C radical resection in our hospital from June 1994 to June 2003, and compared the recurrence and prognosis after transfusion and non-transfusion. Results The recurrence rate of the transfusion group was higher than that of the non-transfusion group (P = 0.034). The transfusion rate was higher than 600ml group (P = 0.037). There was no significant difference between the two groups (P = 0.458). Conclusion Blood transfusion can increase the recurrence rate of patients with rectal cancer, shorten the postoperative tumor-free survival, clinical blood should be carefully weighed.