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我院3年来抢救有机磷中毒508例,发生阿托品依赖18例,发生率3.5％。现分析如下,以探讨其原因。发生机理及临床特征。 1 临床资料 1.1 资料来源与选择标准 本组18例来源于我院3年来收治的508例急性有机磷中毒资料完整者。 (1)经积极抢救治疗,病人达阿托品化后病情明显好转;(2)服毒时间10天以上;(3)阿托品减量或停药时出现头晕、恶心、呕吐、腹痛、胸闷、出汗。个别患者出现心动过缓,血压下降;(4)ChE>30u;(5)排除洗胃不彻底及毒物持续吸收情况。
508 cases of organophosphate poisoning in our hospital in 3 years, 18 cases of atropine dependence occurred, the incidence rate was 3.5%. Now analyze as follows to explore the reasons. Occurrence mechanism and clinical features. 1 Clinical data 1.1 sources and selection criteria 18 cases in this group from our hospital for 3 years admitted 508 cases of acute organophosphate poisoning complete data. (1) After active rescue treatment, the patient’s condition was markedly improved after dalteparinization; (2) She took poison for more than 10 days; and (3) dizziness, nausea and vomiting, abdominal pain, chest tightness and sweating occurred during the reduction or withdrawal of atropine. Individual patients with bradycardia, blood pressure decreased; (4) ChE> 30u; (5) to exclude incomplete gastric lavage and persistent absorption of poisoning.