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作者回顾分析了1979至1985年在美国Nebroska州医学中心接受手术和术后体外放疗的76例晚期头颈部鳞癌病人的局部控制率。其中口腔癌13例、口咽癌14例、梨状窝癌18例、下咽部癌1例、声门上癌21例、喉癌9例。大多数病人发病年龄在60~70岁,均经组织学检查证实为鳞状细胞癌。分化良好至中等分化44例,分化差或未分化32例。40%有颈淋巴结转移。19例口腔和口咽部癌行扩大扁桃体切除术或口底广泛切除并半侧下颌骨切除术和/或半舌切除术,3例行局部广泛切除术,5例行扩大扁桃体切除术。5例声门上癌行声门上喉切除术,16例行全喉切除术。喉
The authors retrospectively analyzed the local control rate of 76 patients with advanced head and neck squamous cell carcinoma who underwent surgery and postoperative external radiotherapy from 1979 to 1985 at the Nebroska State Medical Center in the United States. There were 13 cases of oral cancer, 14 cases of oropharyngeal cancer, 18 cases of pyriform sinus carcinoma, 1 case of hypopharyngeal carcinoma, 21 cases of supraglottic carcinoma, and 9 cases of laryngeal carcinoma. The majority of patients age 60 to 70 years old and were confirmed by histological examination as squamous cell carcinoma. Well-differentiated to moderately differentiated in 44 cases, poorly differentiated or undifferentiated in 32 cases. 40% have cervical lymph node metastases. Nineteen patients with oral and oropharyngeal cancer underwent extensive tonsillectomy or extensive resection of the floor of the mouth and hemi-mandibular resection and/or partial resection of the tongue. Three patients underwent extensive local resection and five patients underwent extended tonsillectomy. Five patients with supraglottic cancer underwent supraglottic resection and 16 underwent total laryngectomy. throat