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目的:调查少数民族地区弓形虫感染状况及其对胎儿的影响。方法:用酶联免疫吸附法(ELISA)检测孕妇血清弓形虫循环抗原(CAg)、IgM及IgG抗体水平。结果:86例病理妊娠的孕产妇中,3项指标阳性40例,阳性率为46.5%,血清中CAg阳性7例,阳性率为8.13%;IgM阳性12例,阳性率为13.95%;IgG阳性21例,阳性率为24.41%。结论:弓形虫感染对胎儿有较大危害,是引起胎儿流产、死胎及畸形的主要原因之一。少数民族地区不同民族孕产妇弓形虫感染率比较差异无统计学意义,孕产妇弓形虫感染率与猫、犬接触史明显相关。基层地区加大孕妇弓形虫感染检测对民族优生优育有较大帮助。
Objective: To investigate the status of Toxoplasma gondii infection and its effect on fetus in ethnic minority areas. Methods: Serum Toxoplasma gondii recurrent antigen (CAg), IgM and IgG were detected by enzyme linked immunosorbent assay (ELISA). Results: Of the 86 pregnant women with pathological pregnancy, 40 were positive for 3 indicators, the positive rate was 46.5%, and the positive rate for serum CAg was 7 cases, the positive rate was 8.13%. IgM was positive in 12 cases, the positive rate was 13.95%. The positive rate of IgG was 21 cases, the positive rate was 24.41%. Conclusion: Toxoplasma gondii infection is more harmful to the fetus, which is one of the main causes of abortion, stillbirth and deformity. There was no significant difference in the infection rates of toxoplasma among different nationalities in ethnic minority areas. The infection rate of Toxoplasma gondii in pregnant women was significantly related to the history of cats and dogs. The detection of Toxoplasma gondii infection in pregnant women in the grassroots areas is of great help to the national eugenics and prenatal education.