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氯霉素作为治疗伤寒病的首选药物已有廿多年的历史。但由于付作用大,治疗后复发率较高,有抗药菌株的出现及不能根除带菌者等的缺点,使其临床应用受到一定的限制。自从1968年以来,不少人认为复方新诺明(TMP+SMZ)治疗伤寒优于氯霉素,其优点为复发率低和付作用少。我院从1977年至1979年曾用此药治疗诊断可靠的伤寒45例。现将临床观察结果分析报导如下:
Chloramphenicol has been the drug of choice for the treatment of typhoid fever for more than 20 years. However, due to large pay, relapse rate after treatment, the emergence of resistant strains and can not eradicate carriers and other shortcomings, its clinical application is subject to certain restrictions. Since 1968, many people think that triamcinolone acetonide (TMP + SMZ) is superior to chloramphenicol in the treatment of typhoid fever, with the advantages of low recurrence rate and less pay. Our hospital from 1977 to 1979 had used this drug in the treatment of typhoid diagnosis of 45 cases. Now clinical analysis of the results reported as follows: