论文部分内容阅读
目的探讨依达拉奉联合亚低温治疗急性重型颅脑损伤临床疗效。方法选取我院2010年5月至2012年10月收治急性重型颅脑损伤患者80例,随机分为两组,对照组40例采用常规的方法进行治疗;治疗组40例在常规治疗的基础上给予依达拉奉联合亚低温进行治疗。对两组患者的脑水肿程度、格拉斯昏迷评分(GCS)以及格拉斯结果(GOS)进行观察和比较。结果治疗14 d后,治疗组脑水肿轻度患者的比例明显高于对照组,重度患者的比例明显低于对照组,治疗后两组患者的GCS评分均高于治疗前,治疗组的GCS评分明显高于对照组,且治疗组患者的GOS等级明显优于对照组,差异均有统计学意义(P<0.05)。结论依达拉奉联合亚低温治疗急性重型颅脑损伤能明显提高患者的治疗有效率,促进患者脑神经功能的恢复。
Objective To investigate the clinical efficacy of edaravone combined with mild hypothermia in the treatment of acute severe traumatic brain injury. Methods 80 cases of acute severe craniocerebral injury admitted to our hospital from May 2010 to October 2012 were randomly divided into two groups, 40 cases in the control group were treated by conventional method. On the basis of routine treatment, 40 cases in the treatment group Edaravone given combined hypothermia for treatment. The degree of brain edema, GCS and GOS in both groups were observed and compared. Results After 14 days of treatment, the proportion of patients with mild brain edema in the treatment group was significantly higher than that in the control group, and the proportion of severe patients was significantly lower than that in the control group. The GCS scores of the two groups after treatment were higher than those before treatment and GCS scores Significantly higher than the control group, and the treatment group patients with GOS grade was significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion Edaravone combined with mild hypothermia in the treatment of acute severe traumatic brain injury can significantly improve the therapeutic efficiency of patients and promote the recovery of patients with neurological function.