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目的探讨病毒性脑炎血清酶学变化的临床意义。方法选择某医院入住的病毒性脑炎患者60例做研究组,抽取静脉血2 mL,抽取时间应为次日晨起,空腹。对天门冬氨酸氨基转移酶(AST)、碱性磷酸酶(ALP)、丙氨酸氨基转移酶(ALT)、γ谷氨酰基转移酶(γ-GT)、肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)、肌酸激酶(CK)、α-羟丁酸脱氢酶(α-HBDH),进行检测,并与80例对照组头痛患者同类酶检测结果进行比较。结果病毒性脑炎组血清酶学变化异常检出率为65%,对照组血清酶学检出率是27%,2组比较差异有统计学意义(P<0.05)。结论对血清酶学进行测定在病毒性脑炎的鉴别和早期诊断上有重要帮助意义。
Objective To investigate the clinical significance of serum enzyme changes in viral encephalitis. Methods Sixty patients with viral encephalitis admitted to a hospital were selected as the study group. 2 mL of venous blood was drawn. The time for extraction should be the next morning and fasting. Aspartate aminotransferase (AST), alkaline phosphatase (ALP), alanine aminotransferase (ALT), γ-glutamyl transferase (γ-GT), creatine kinase isoenzyme (CK -MB), lactate dehydrogenase (LDH), creatine kinase (CK) and α-hydroxybutyrate dehydrogenase (α-HBDH) were measured and compared with the results of similar enzymes in headache patients of 80 control subjects . Results The positive rate of serum enzyme changes was 65% in viral encephalitis group and 27% in control group. The difference between the two groups was statistically significant (P <0.05). Conclusion The determination of serum enzymology is of great help in the differential diagnosis and early diagnosis of viral encephalitis.