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目的:对亲属活体供肾的优点和临床意义进行探讨。方法:总结19例亲属活体供肾肾移植临床资料。其中,男性受体11例,女性受体8例,年龄20~50岁,平均28.6岁;男性供体10例,女性供体9例,年龄38~62岁,平均52.8岁。结果:19例中有16例术后2~5d肾功能恢复正常,另外3例中,其中1例术后1周出现急性排斥反应,经抗排斥治疗,3周后移植肾功能恢复正常。1例术后2个月发现移植肾输尿管膀胱吻合口狭窄,行输尿管再植后肾功能恢复,1例术后出现肾功能恢复延迟。结论:术前全面地对供受者进行全面的体检和化验是亲属活体肾移植术后成功的保证。亲属肾移植的组织配型好,供肾缺血时间短,排斥反应发生少,免疫抑制剂用量少,移植效果优于尸肾移植,且能缓解肾源短缺。
Objective: To investigate the advantages and clinical significance of living donor kidney. Methods: The clinical data of 19 relatives living donor kidney transplantation were summarized. Among them, there were 11 male and 8 female recipients, ranging in age from 20 to 50 years with an average of 28.6 years. There were 10 male donors and 9 female donors. The average age was 52.8 years. Results: Sixteen of 19 patients returned to normal function 2 to 5 days after operation. In the other 3 cases, 1 case showed acute rejection 1 week after operation. After 3 weeks, the function of renal allograft returned to normal. One case was found 2 months after transplantation, ureteric anastomotic stricture ureter, renal function recovery after ureteral replantation, delayed recovery of renal function in 1 case. CONCLUSIONS: A comprehensive preoperative and postoperative comprehensive medical examination and laboratory test is a guarantee of success after living donor kidney transplantation. Kidney transplantation relatives with good tissue distribution, for a short period of ischemia, ischemia rejection, immunosuppressive agents with less transplantation better than cadaveric kidney transplantation, and can alleviate the shortage of kidney.