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目的:探讨提高中枢神经细胞瘤的诊疗水平。方法:回顾分析2004年8月至2006年4月我院收治的5例中枢神经细胞瘤,总结其临床表现、影像学表现、病理学特征及显微外科手术治疗效果。结果:肿瘤位于侧脑室前部或室间孔附近,呈宽基底与侧脑室壁或透明隔相连。肿瘤边缘及内部可见多发囊泡,常见钙化,MRI上实性部分T1WI、T2WI均表现为等或略高信号,增强后呈轻至中度强化。免疫组织化学染色均显示神经突触素阳性。显微外科手术治疗5例,其中全切除4例,次全切除1例,1例死于术后并发症,4例随访至今未复发。结论:中枢神经细胞瘤影像学表现具有一定特征性,是术前诊断的重要方法。显微手术切除肿瘤是最佳的治疗手段,预后良好。
Objective: To explore the diagnosis and treatment of central neurocytoma. Methods: Five cases of central neuroblastoma in our hospital from August 2004 to April 2006 were retrospectively analyzed. The clinical manifestations, imaging findings, pathological features and microsurgical treatment were summarized. Results: The tumor was located in the anterior part of the lateral ventricle or near the interventricular foramen, forming a wide basement connected with the lateral ventricle wall or the translucent septum. Tumors at the edge and the internal visible multiple vesicles, common calcification, MRI T1WI real part, T2WI showed equal or slightly higher signal enhanced enhanced mild to moderate enhancement. Immunohistochemical staining showed synaptophysin-positive. Five cases were treated by microsurgery, including 4 cases underwent total resection, 1 case underwent subtotal resection, 1 case died of postoperative complications, and 4 cases had no recurrence after follow-up. Conclusion: Imaging features of central neurocytoma have certain characteristics and are important methods of preoperative diagnosis. Microsurgical resection of the tumor is the best treatment, the prognosis is good.