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女性胆囊结石的发病率是男性的2～3倍、雌性激素类药物的应用可使胆囊结石的发病率上升，提示雌性激素与胆囊结石的发病有密切关系。我们于1995年IO月～1996年11月对71例女性胆囊结石患者进行了血清雌二醇（EZ）、孕酮（P）测定，旨在探讨雌性激素在女性胆囊结石发病中的作用。
The incidence of female gallstones is 2 to 3 times that of men, the application of estrogen drugs can increase the incidence of gallstones, suggesting that estrogen is closely related to the incidence of gallstone. We measured the serum estradiol (EZ) and progesterone (P) in 71 women with gallstone from October 1995 to November 1996 to investigate the role of estrogen in the pathogenesis of gallstone in women.