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新生儿破伤风,目前在我国农村偏僻落后地区还常有发生,国内病死率高达50～60%,严重威胁着新生儿的健康和生命。本病致死的直接原因是肌肉强烈痉挛和窒息,故制止痉挛是降低病死率的关键性环节。笔者就近几年来用大剂量安定鼻饲法为主治疗新生儿破伤风24例与以往未用大剂量安定治疗的19例作为对照进行疗效分析。一、临床资料本组病例男16例,女8例。发病3～4日者2例,5～7日者18例,8～10日者2例,12日及14日各1例。这些患儿均来自农村医疗条件落后地区,均为消毒不严密或不消毒方法接生。临床上都有牙关紧闭,不能吮乳,苦笑面容,肌强硬和肌痉挛,均在48小时以内入院。24例合并肺炎者8例,其中4例同时合并心衰。合并新生儿硬肿症者4例。对照组19例与以上临床资料相似,具有可比性.
Neonatal tetanus, which is still common in remote and backward rural areas in China, has a mortality rate of 50-60% in China, which seriously threatens the health and life of the newborn. The direct cause of death of this disease is muscle spasms and asphyxia, so to prevent cramps is to reduce the mortality of the key link. In recent years, the author used large doses of stable nasal feeding method for the treatment of neonatal tetanus in 24 cases and in the past did not use high-dose stability of 19 cases treated as a control efficacy analysis. First, clinical data The group of 16 males and 8 females. The incidence of 3 to 4 days in 2 cases, 5 to 7 days in 18 cases, 8 to 10 days in 2 cases, 12 and 14 days in 1 case. These children were from rural areas in backward medical conditions, are not strict disinfection or non-sterile delivery methods. Clinical clinically closed, can not suck milk, smile face, muscle stiffness and muscle spasm, were admitted within 48 hours. Of the 24 patients with pneumonia, 8 were complicated by heart failure. 4 cases of merger neonatal sclerosing. The control group of 19 cases with similar clinical data, comparable.