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目的：探讨美蓝染色对胃良恶性病变的定牲及判定癌浸润深度的价值。方法：将０．３％美蓝用喷洒管经内镜直接在病变处喷洒染色。结果：５３例中Ⅰ型６例，Ⅱ ａ型６例，Ⅱ ａ＋Ⅱｃ型４例，Ⅱｃ型６例，Ⅲ型１９例，Ⅱｃ＋Ⅲ型１２例；粘膜内癌 ２４例，粘膜下癌 ２９例。染色后对癌浸润深度判断的准确率为粘膜内癌 ８２．５％，粘膜下癌 ８６．２％。结论：美蓝染色可使病变更加清晰，增加立体感，补充肉眼观察的不足，对鉴别病变的良恶性及判定癌浸润深度具有重要的价值。
OBJECTIVE: To investigate the value of methylene blue staining in the determination of benign and malignant gastric lesions and to determine the depth of cancer invasion. METHODS: 0.3% Methylene blue was sprayed directly through the endoscope at the lesion. RESULTS: Among the 53 cases, there were 6 cases of type I, 6 cases of type IIa, 4 cases of type IIa+IIc, 6 cases of type IIc, 19 cases of type III, 12 cases of type IIc+III, 24 cases of intramucosal carcinoma and 29 cases of submucosal carcinoma. The accuracy of judging the depth of invasion after staining was 82.5% in intramucosal cancer and 86.2% in submucosal cancer. Conclusion: Methylene blue staining can make the lesion more clear, increase the three-dimensional sensation, and supplement the insufficiency of macroscopic observation, which is of great value in distinguishing benign and malignant lesions and judging the depth of cancer invasion.