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Warthin氏1913年报告有关癌的遗传因素以来,癌症的家族性问题越来越引起了人们的关注。我国启东县1972年对肝癌家族聚集性回顾性调查中也证明肝癌有家族聚集象,但一家两代患3例原发性肝癌报道不多,现报道如下: 例一,长子,45岁,工人,离家到机关工作22年,住院号78613,因上腹部反复疼痛4年,近两个月来加重,并有眼黄、尿黄、食欲减少,身体明显消瘦及腹部进行性增大而于1972年8月19日入院。查体:慢性病容,全身皮肤干燥,皮下脂肪消失,胸部偶见不典型蜘蛛痣,两巩膜黄染,表浅淋巴结不大,心肺无异常,腹部膨隆,触诊有波
Since Warthin’s 1913 report on the genetic factors of cancer, familial problems of cancer have attracted more and more attention. The retrospective investigation of the family aggregation of liver cancer in Qidong County, China in 1972 also showed that there were family clusters of liver cancer. However, there were few reports of two cases of primary liver cancer in two generations. Here are the reports as follows: Example 1, eldest son, 45 years old, worker After leaving home for 22 years, the hospital number is 79613, due to repeated abdominal pain for 4 years, heavier in the last two months, with yellow eyes, urine yellow, decreased appetite, marked body thinning, and progressive abdominal enlargement. He was admitted to hospital on August 19, 1972. Physical examination: chronic disease, dry body skin, subcutaneous fat disappeared, occasional atypical spider axillae on the chest, two yellow sclera, superficial lymph nodes, no abnormalities in heart and lung, abdominal distention, palpation wave