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绪言和历史回顾从十八世纪后半期起。脑循环的生理和药理已引起许多研究者的兴趣。现代脑血流量(CBF)的研究从1925年开始分为四期。在第一期中,直到1945年以前.定性的或充其量不过是半定量的研究方法发展了,例如通过颅骨窗藉显微镜测量软脑膜动脉的直径,但仅可用于动物实验。然而这期间是有成果的,因为在此期中研究了脑循环的许多生理和病理反应,包括血压改变的影响,软脑膜血管的局部用药,或胃肠道外用药的影响,自主神经系统的某些
Introduction and historical review from the latter half of the eighteenth century. The physiology and pharmacology of the cerebral circulation has attracted the interest of many researchers. The study of modern cerebral blood flow (CBF) has been divided into four phases since 1925. In the first phase until 1945, qualitative or at best semi-quantitative research methods were developed, for example by measuring the diameter of the pial artery by means of a cranial window microscope, but only for animal experiments. However, this period was fruitful because many of the physiological and pathological responses to the cerebral circulation were studied during this period, including the effects of changes in blood pressure, local administration of pial vessels, or effects of parenteral administration, some of the autonomic nervous system