我们对13例硬皮病患者进行了电子显微镜观察,结果如下。材料和方法13例中局限性硬皮病1例,系统性硬皮病12例(弥漫型6例,肢端型6例)。局限性患者为女性,35岁,病期一年。皮疹多发,分布于前胸、右侧腹部及右下肢,呈浅褐色,坚而硬的斑块,表面皮肤萎缩,发亮。12例系统性硬皮病患者,女11 We observed 13 cases of scleroderma by electron microscopy, the results are as follows. Materials and methods 13 cases of localized scleroderma in 1 case, systemic scleroderma in 12 cases (diffuse 6 cases, acral 6 cases). The limitations of patients for women, 35 years old, the disease period of one year. Multiple rashes, located in the chest, right abdomen and right lower limb, was light brown, hard and hard plaques, the surface of the skin atrophy, shiny. 12 patients with systemic scleroderma, female 11