Somatic second-hit mutations leads to polycystic liver diseases

来源 :世界胃肠病学杂志：英文版（电子版） | 被引量 : 0次 | 上传用户：yuekinger

【摘要】

：

Polycystic liver diseases(PCLDs) are a heterogeneous group of genetic disorders characterized by the development of multiple fluid-filled cysts in the liver,whi

【作者】

：

Jesús M Banales Patricia

【机构】

：

DivisionofHepatologyandGastroenterology,DepartmentofLiverandGastrointestinalDiseases,Ikerbasque,Span

【出处】

：

世界胃肠病学杂志：英文版（电子版）

【发表日期】

：

2013年1期

【关键词】

：

POLYCYSTIC liver diseases CHOLANGIOCYTE Cystogenesis Loss of HETEROZYGOSITY Prot

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Polycystic liver diseases(PCLDs) are a heterogeneous group of genetic disorders characterized by the development of multiple fluid-filled cysts in the liver,which derive from cholangiocytes,the epithelial cells lining the bile ducts.When these cysts grow,

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Somatic second-hit mutations leads to polycystic liver diseases

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