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目的 对慢性支气管炎急性期和缓解期患者外周血B细胞和T细胞CD分子检测并了解其变化。方法 用荧光单抗CD19+、CD4 +、CD8+/CD2 8+对B细胞和T细胞亚群进行标记和记数。结果 慢性支气管炎急性发作期患者与缓解期患者相比 ,体内辅助性T淋巴细胞无明显变化 ,抑制性T淋巴细胞增加 ,细胞毒性T淋巴细胞减少 ,B淋巴细胞二者间无差异。结论 因慢性支气管炎急性期危重病人T淋巴细胞亚群变化 ,造成免疫功能紊乱。因此 ,在治疗疾病过程中 ,除对症处理外 ,另须配合使用提高免疫功能的药物 ,改善免疫功能
Objective To detect and understand the CD molecules of B cells and T cells in peripheral blood of patients with chronic bronchitis in acute phase and remission. Methods The B cells and T cell subsets were labeled and labeled with fluorescent monoclonal antibodies CD19 +, CD4 +, CD8 + / CD2 +. Results There was no significant difference in the number of T helper cells, the increase of inhibitory T lymphocytes, the decrease of cytotoxic T lymphocytes and B lymphocytes in patients with acute exacerbation of chronic bronchitis compared with patients in remission. Conclusion Due to the changes of T lymphocyte subsets in critically ill patients with chronic bronchitis, immune dysfunction is caused. Therefore, in the treatment of disease, in addition to symptomatic treatment, the other with the use of drugs to enhance immune function, improve immune function