论文部分内容阅读
目的:探讨影响恶性梗阻性黄疸经皮肝穿胆道引流(PTBD)联合胆道支架置入术(PTBS)短期疗效的相关因素。方法:分析2004年6月—2009年6月经PTBD和PTBS治疗的恶性梗阻性黄疸患者107例,参照胆红素下降程度和术后30 d内生存情况分为短期治疗有效(91例)和无效(16例)2组,应用卡方检验进行单因素分析,非条件Logistic进行多因素分析。结果:单因素分析显示患者年龄、性别、梗阻时间、梗阻部位、术前胆道感染和肝功能Child-Pugh评分、TBIL、HGB、Cr 9个因素与恶性梗阻性黄疸介入治疗预后相关。多因素分析示术前胆道感染、肝功能Child-Pugh评分≥9分、Cr≥111μmol/L是恶性梗阻性黄疸介入治疗的高危因素。结论:术前胆道感染、肝功能Child-Pugh评分≥9分、Cr≥111μmol/L与恶性梗阻性黄疸短期预后关系密切,对梗阻性黄疸介入治疗的术前评估有重要参考意义。
Objective: To investigate the related factors that affect the short-term efficacy of percutaneous transhepatic biliary drainage (PTBD) combined with biliary stenting (PTBS) in patients with malignant obstructive jaundice. Methods: A total of 107 patients with malignant obstructive jaundice treated with PTBD and PTBS from June 2004 to June 2009 were divided into short-term effective treatment (91 cases) and ineffective (16 cases) were divided into two groups. Univariate analysis was performed by chi-square test and multivariate analysis was performed by non-conditional Logistic. Results: Univariate analysis showed that 9 factors including age, gender, obstruction time, site of obstruction, preoperative biliary tract infection and liver function Child-Pugh score, TBIL, HGB and Cr were correlated with prognosis of malignant obstructive jaundice interventional therapy. Multivariate analysis showed that preoperative biliary tract infection, liver function Child-Pugh score ≥ 9 points, Cr ≥ 111μmol / L is a risk factor for interventional treatment of malignant obstructive jaundice. Conclusion: Preoperative biliary tract infection, liver function Child-Pugh score ≥ 9 points, Cr ≥ 111μmol / L and malignant obstructive jaundice short-term prognosis are closely related to the interventional treatment of obstructive jaundice has important reference significance.