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沙眼衣原体（Ct）是专性胞内生长的细菌。用细胞培养，PCR和DNA序列分析对母婴Ct感染进行了前瞻性研究。共对278名孕妇宫颈、78名随访婴儿和45名肺炎患儿睑结膜、鼻咽标本行检测。培养示宫颈Ct阳性率10.8％（30/278），而PCR阳性率14％（39/278）。与培养比较，PCR检测宫颈标本的特异性、敏感性、阳性预测值（PPV）、阴性预测值（NPV）各是100％、95.5％、76.9％和100％；20名生于宫颈Ct阳性母亲的婴儿中11名感染了Ct，而59名生于未感染母亲的婴儿无1例发生Ct感染。两组婴儿Ct感染发生率差异显著（P＜0.005）。母婴Ct传播率为55％
Chlamydia trachomatis (Ct) is a specialized intracellular growth of bacteria. Prospective studies of Ct infection in mothers and infants were performed using cell culture, PCR and DNA sequence analysis. A total of 278 pregnant women cervix, 78 follow-up infants and 45 children with conjunctival pneumonia, nasopharyngeal specimens were detected. Culture showed cervical Ct positive rate of 10.8% (30/278), and PCR positive rate of 14% (39/278). The specificity, sensitivity, positive predictive value (PPV) and negative predictive value (NPV) of PCR in cervical specimens were 100%, 95.5%, 76.9% and 100%, respectively. Of the infants were infected with Ct, and none of the 59 infants born to uninfected mothers developed Ct infection. The incidence of Ct infection was significantly different between the two groups (P <0.005). Mother and child Ct transmission rate of 55%