论文部分内容阅读
目的评价加替沙星治疗老年社区获得性肺炎的疗效和安全性。方法40例患者接受加替沙星400mg静脉滴注治疗,每日1次;38例患者接受左氧氟沙星500mg静脉滴注治疗,每日1次;30例患者接受环丙沙星200mg静脉滴注治疗,每日2次;疗程均为7~14d。结果加替沙星组、左氧氟沙星组痊愈率和有效率分别为80%、79%与95%、92%(P>0.05),加替沙星组、环丙沙星组痊愈率和有效率分别为80%、60%与95%、73%(P<0.05)。结论国产加替沙星抗菌谱广,抗菌活性强,副作用小,且疗效明显优于环丙沙星,能安全有效地治疗老年社区获得性肺炎,有较高的临床应用价值。
Objective To evaluate the efficacy and safety of gatifloxacin in the treatment of elderly community-acquired pneumonia. Methods 40 patients received gatifloxacin 400mg intravenously once a day, 38 patients received levofloxacin 500mg intravenously once a day, 30 patients received 200mg intravenous infusion of ciprofloxacin, 2 times a day; treatment are 7 ~ 14d. Results In the gatifloxacin group, the cure rates and effective rates of levofloxacin group were 80%, 79% and 95%, 92%, respectively (P> 0.05). The cure rate and effective rate of gatifloxacin group and ciprofloxacin group were 80%, 60% and 95%, 73% (P <0.05). Conclusion The domestic gatifloxacin antibacterial spectrum is broad, antibacterial activity is strong, side effects are small, and the curative effect is obviously superior to ciprofloxacin, can safely and effectively treat the elderly community-acquired pneumonia, and has high clinical value.