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患者，女性、48岁，于1990年7月下旬无明显诱因突发腹泻，在当地医院诊断为急性胃肠炎，分别给予磺胺等抗生素治疗近2月无效而到医院就诊。病人有类风湿性关节炎病史，长期服用强的松或地塞米松，病前半年突然停用。停药后四肢关节痛疼加重。查体：体温36.4℃，皮肤弹性减弱，可见较多褐色色素斑，尤以双下肢为明显。全腹轻压痛，无反跳痛及肌紧张，肠鸣音活跃。双手指关节梭形畸形，僵硬，活动受限。化验：白细胞14.1×10~9/L，中性0.8，淋巴0.2；血沉65mm/h；大便常规：黄稀便，白细胞++/高；血电解质：钾2.85mmol/
Patient, female, 48 years old, had no predisposing sudden diarrhea in late July 1990 and was diagnosed with acute gastroenteritis in a local hospital. Antibiotics such as sulfonamides were given to the hospital for treatment within two months. Patients have a history of rheumatoid arthritis, long-term use of prednisone or dexamethasone, sudden withdrawal six months before illness. After the withdrawal of limbs joint pain worse. Physical examination: body temperature 36.4 ℃, weakened skin elasticity, showing more brown pigmentation spots, especially in both lower extremities. Full abdominal tenderness, no rebound tenderness and muscle tension, bowel sounds active. Two-finger joint fusiform deformity, stiffness, limited mobility. Laboratory: white blood cells 14.1 × 10 ~ 9 / L, neutral 0.8, lymphatic 0.2; erythrocyte sedimentation rate 65mm / h; stool routine: yellow loose stools, white blood cells ++ / high; electrolytes: potassium 2.85mmol /