患者女,76岁。外阴增生物伴疼痛3个月。既往有硬化性萎缩性苔藓病史10余年。皮损组织病理示:角化过度,角化不全,表皮增生,表皮基底部细胞向下增生,细胞排列轻度紊乱,局部可见真皮浅层鳞状细胞团块,可见角化不良细胞及核异型性,真皮乳头层不等量淋巴细胞为主浸润。诊断:外阴鳞状细胞癌;外阴硬化性萎缩性苔藓。 Female patient, 76 years old. Vulva proliferators with pain for 3 months. Previous history of sclerosing lichenification more than 10 years. Histopathological examination of the lesion revealed hyperkeratosis, hyperkeratosis, hyperplasia of epidermis, downward hyperplasia of cells in the epidermis basal cell line, mild disorder of cell arrangement, superficial squamous cell mass in the dermis, showing that the keratinocytes and the nuclear atypia Sexual, dermal papillary layers ranging from the main infiltration of lymphocytes. Diagnosis: vulvar squamous cell carcinoma; vulvar sclerosis atrophic moss.