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目的:探讨腹腔镜保守性手术后用中药治疗子宫内膜异位症合并不孕的临床疗效。方法:60例随机分为中药组35例和西药组25例,分别用中药化瘀消癥汤及西药孕三烯酮治疗,比较术后应用化瘀消癥汤和孕三烯酮的疗效、妊娠率、不良反应及复发情况。结果:两组症状都得到不同程度的缓解,两组总有效率分别为85.72%和84.00%,差异无统计学意义(P>0.05),中药组术后1年内妊娠率为60.00%,西药组术后1年内妊娠率为32.00%,两组比较有显著性差异(P<0.05)。中药组及西药组复发率分别为11.42%和12.00%,差异无统计学意义(P>0.05)。结论:中药化瘀消癥汤用于盆腔子宫内膜异位症保守性手术后的巩固治疗可预防和减少复发,调节内分泌,提高妊娠率,且不良反应小。
Objective: To investigate the clinical efficacy of traditional Chinese medicine in the treatment of endometriosis complicated with infertility after laparoscopic conservative surgery. Methods: Sixty cases were randomly divided into three groups: 35 cases in the traditional Chinese medicine group and 25 cases in the western medicine group. The treatment groups were treated with traditional Chinese medicine Huayu Xiaozheng Decoction and western medicine gestrinone respectively. The curative effect of Huayu Xiaozheng Decoction and Gestrinone were compared. Pregnancy rate, adverse reactions and recurrence. Results: The symptoms of both groups were relieved to some extent. The total effective rates of the two groups were 85.72% and 84.00% respectively, with no significant difference (P> 0.05). The pregnancy rate of the Chinese medicine group within one year after operation was 60.00% The pregnancy rate was 32.00% within 1 year after operation, showing significant difference between the two groups (P <0.05). The recurrence rates of Chinese medicine group and western medicine group were 11.42% and 12.00%, respectively, with no significant difference (P> 0.05). Conclusion: The treatment of conservative treatment of pelvic endometriosis after conservative treatment of pelvic endometriosis can prevent and reduce recurrence, regulate endocrine, improve pregnancy rate, and the adverse reaction is small.