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本研究目的是确定孕4～6个月时发现胎儿有NTD的孕妇是否存在锌缺乏,并与无胎儿NTD的正常孕妇及有血AFP升高的孕妇锌水平进行比较。研究包括30例19～36岁健康、未服OC的非孕妇女;69例18～35岁的正常孕妇(其中31例孕16±3周、38例孕35±3.5周),血AFP水平正常,正常妊娠且分娩正常婴儿;22例17～35岁孕17.5±4周孕妇中20例血AFP水平高于同期孕妇平均值2倍以上,一周后复查AFP仍高且可排除多胎及宫内死亡等因素,其中4例及另2例血AFP水平正常的孕妇在超声检查时发现胎儿有NTD。对所有研究对象于早上9～11点钟时取静脉血,用葡聚糖沉
The aim of this study was to determine if zinc deficiency exists in pregnant women with NTD at 4 to 6 months of gestation and to compare zinc levels in pregnant women with normal NTD without fetal and pregnant women with elevated serum AFP. The study included 30 healthy non-OC pregnant women aged 19-36 years; 69 normal pregnant women aged 18-35 (31 pregnant, 16 ± 3 weeks and 38 pregnant, 35 ± 3.5 weeks) with normal blood AFP levels , Normal pregnancy and delivery of normal infants; 22 cases of 17-35-year-old pregnant 17.5 ± 4 weeks pregnant women 20 cases of blood AFP levels higher than the average of the same period more than 2 times the pregnant women, a week after the review AFP is still high and can eliminate multiple births and intrauterine death And other factors, of which 4 cases and 2 cases of normal blood AFP levels of pregnant women in the ultrasound examination found that the fetus has NTD. Venous blood was taken from 9 to 11 in the morning for all subjects, and dextran was used