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白三烯抑制剂ＳＫ＆Ｆ－１０４３５３最近报道了ＳＫ＆Ｆ－１０４３５３的一个新的对映选择性合成方法。该化合物可用两种相关的方法制备：方法一：２－（８－苯基辛基）苯甲醛（１）和２－萘乙酮（Ⅱ）在乙醇钠的作用下于乙醇中缩合，生成（Ｅ）－１－（２－萘基）－３－...
Leukotriene inhibitor SK & F-104353 recently reported a new enantioselective synthesis of SK & F-104353. The compound can be prepared by two related methods: Method one: 2- (8-phenyloctyl) benzaldehyde (1) and 2-acetonaphthone (II) are condensed in ethanol under sodium ethoxide to give ( E) -1- (2-naphthyl) -3 -...