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本文观察了24例糖尿病血小板还原型谷胱甘肽(GSH)浓度变化、血小板聚集及血浆ⅧR:Ag水平,并对血小板GSH含量与血小板聚集性之间的相互关系进行了分析。 对象与方法 一、病例选择:我院门诊及住院确诊糖尿病患者24例(按1979年全国糖尿病研究专题会议提出的诊断标准)。其中男13例,女11例,平均年龄41.3岁(范围11～63岁),平均病程4.02年(范围2月～11年)。其中有血管病变16例,无血管病变8例。除饮食疗法外,10例接受胰岛素,12例接受口服降糖药治疗。正常对照组20例,系本院血库献血员及健康职工,其中男11例,女9例,平均年龄40岁(范围17～62岁)。
In this paper, 24 cases of diabetic platelet reduced glutathione (GSH) concentration changes, platelet aggregation and plasma Ⅷ R: Ag levels, and platelet GSH content and platelet aggregation were analyzed. Subjects and methods First, the case selection: 24 cases of outpatient and inpatient diabetes mellitus in our hospital (according to the diagnostic criteria proposed by the National Diabetes Research Conference in 1979). There were 13 males and 11 females with an average age of 41.3 years (range 11-63 years) with an average duration of 4.220 years (range, February to 11 years). Including 16 cases of vascular lesions, vascular disease in 8 cases. In addition to diet therapy, 10 patients received insulin and 12 patients received oral hypoglycemic agents. Normal control group of 20 cases, Department of blood donation and health workers in our hospital, including 11 males and 9 females, mean age 40 years (range 17 to 62 years old).