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目的了解我院门诊病人的药品不良反应(ADR)发生情况。方法对2006～2008年我院门诊发生的ADR病例进行统计分析。结果245例ADR中涉及药物63种;抗生素引发者最常见,占60.00%(147/245);其次为中药类针剂,占26.53%(65/245);发生时间最短为用药后7秒钟、最长9天;临床表现以皮肤及其附件损害为主。原发病以呼吸系统疾病为主,占53.87%(132/245)。结论重视门诊ADR监测,对门诊病人进行用药不良反应的风险告知及宣教,可预防或减少ADR的发生。
Objective To understand the adverse drug reaction (ADR) in outpatients in our hospital. Methods The incidence of ADR cases in our hospital from 2006 to 2008 were analyzed statistically. Results Among the 245 ADRs, 63 drugs were involved. Antibiotics were the most common initiators, accounting for 60.00% (147/245). Followed by traditional Chinese medicine injections (26.53%, 65/245). The shortest occurrence time was 7 seconds after treatment, Up to 9 days; the main clinical manifestations of damage to the skin and its accessories. The primary disease was mainly respiratory diseases, accounting for 53.87% (132/245). Conclusions Emphasis on outpatient ADR monitoring, outpatient risk of adverse reactions to medication and education, can prevent or reduce the occurrence of ADR.