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目的：探讨早期应用运动疗法对股骨骨折内固定术后患者的影响。方法：选择78例股骨骨折患者，并行股骨干骨折切开复位内固定术。随机分为治疗组和对照组。治疗组早期应用运动疗法，对照组中晚期运用运动疗法，记录两组患者肿胀开始消退时间，测定术后8周膝关节活动范围及骨折愈合情况。结果：治疗组患者的肿胀开始消退时间（3.87±0.214天）为较对照组（6.29±0.203天）明显提前，差异具有统计学意义（P＜0.05）。治疗组在术后8周R O M为（91.66±11.443°），较对照组（43.92±7.638°）显著提高，差异具有统计学意义（P＜0.05）。治疗组骨折愈合程度为（7.697±2.0416）较对照组（6.711±0.3593）明显改善，差异具有统计学意义（P＜0.05）。结论：早期运动疗法可缩短股骨干骨折患者患肢肿胀开始消退时间，促进术后患侧膝关节功能恢复，对骨折愈合具有促进作用。“,”Objective: To investigate the effect of early application of exercise therapy on patients with femoral fractures after internal fixation. Methods: 78 cases of patients with fracture of femur were randomly divided into treatment group and control group. Femoral shaft fracture with open reduction and internal fixation were performed for these patients. Treatment group received exercise therapy at early stage, while control group received it at late stage. The time of swel ing began to subside was recorded. After 8 weeks post-operation, range of motion (ROM) of knee joint was measured and fracture healing was evaluated. Results: The time of swel ing began to subside in treatment group (3.87±0.214 days) was significantly ahead of schedule compared with the control group (6.29±0.203 days), the difference was statistical y significant (P<0.05). The (ROM) in treatment group (91.66±11.443°)was significantly increase compare with control group(43.92±7.638°) after 8 weeks post-operation, the difference was statistical y significant (P<0.05). The degree of fracture healing in treatment group (7.697±2.0416) improved obviously than control group (6.711±0.3593), the difference was statistical y significant (P<0.05). Conclusion: Early exercise therapy can shorten the time of swel ing began to subside in patients with femoral shaft fracture, promote the recovery of postoperative knee joint function and promote the healing of fracture.