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目的 探讨新生儿反复呼吸暂停与缺氧性脑损伤的关系。方法 对 78例反复呼吸暂停新生儿进行头颅CT扫描 ,其中足月儿 2 8例 ,早产儿 5 0例。观察缺氧性脑损伤的发生情况。结果 蛛网膜下腔出血 (SAH)2 5例 ,脑室内出血 (IVH) 10例 ,缺氧缺血性脑病 (HIE) 6例 ,HIE +SAH 8例 ,总阳性率为 6 2 .8%。早产儿组阳性率为 74% ,以颅内出血为主 ,足月儿组阳性率为 42 .8% ,以HIE及SAH为主。早产儿组与足月儿组比较差异有显著性意义 (P <0 .0 1)。结论 新生儿反复呼吸暂停 ,是新生儿出生后缺氧性脑损伤的早期表现之一。对此类新生儿尤其是早产儿进行头颅CT扫描 ,有助于脑损伤的早期诊断与治疗。
Objective To investigate the relationship between neonatal repeated apnea and hypoxic brain injury. Methods Totally 78 neonates with repeated apnea were screened by CT, of which 28 were full-term infants and 50 were premature infants. Observe the occurrence of hypoxic brain injury. Results 25 cases of subarachnoid hemorrhage (SAH), 10 cases of intraventricular hemorrhage (IVH), 6 cases of hypoxic-ischemic encephalopathy (HIE), 8 cases of HIE + SAH, the total positive rate was 62.8%. The positive rate of preterm children was 74%, with intracranial hemorrhage as the mainstay. The positive rate of full-term children was 42.8%, mainly HIE and SAH. There was significant difference between premature infant group and full term infant group (P <0.01). Conclusions The neonatal repeated apnea is one of the early manifestations of neonatal hypoxic brain injury after birth. CT scan of such newborns, especially premature infants, is helpful for the early diagnosis and treatment of brain injury.