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作者根据他的临床试用结果,认为羟氨喹(UK4271)是治疗曼氏血吸虫病极为有效的药物。作者用羟氨喹7.5毫克/公斤体重,单剂,肌肉注射,治疗53例曼氏血吸虫病,治愈率高达92.7%。肌肉注射有局部疼痛的严重缺点,现已改用口服疗法。第1组20例,10毫克/公斤体重,单剂口服,疗效为70.0%。第2组26例,12.5毫克/公斤体重,单剂口服,疗效为80.8%。第3组30例,15毫克/公斤体重,单剂口服,疗
Based on his clinical trial results, the authors believe that hydroxyquine (UK4271) is an extremely effective drug for the treatment of Schistosoma mansoni. The authors used hydroxylamine quinoline 7.5 mg / kg body weight, single dose, intramuscular injection, the treatment of 53 cases of schistosomiasis, the cure rate as high as 92.7%. Muscle injection has serious shortcomings of local pain, has now been switched to oral therapy. Group 1 20 cases, 10 mg / kg body weight, single oral, the effect was 70.0%. Group 2 26 cases, 12.5 mg / kg body weight, single oral dose, the effect was 80.8%. Group 3 30 cases, 15 mg / kg body weight, single oral administration