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患者女,76岁。右颞部溃疡逐渐增大5年,加重2个月。皮损表现为右颞部一7cm×5cm大小溃疡,边界清楚,呈堤状隆起,表面伴脓血性分泌物,右耳后一2cm×2cm暗红色肿物。皮损组织病理示:表皮大致正常,真皮浅层见大片肿瘤细胞团块,呈分叶状分布,未与表皮相连,团块边缘肿瘤细胞呈栅栏状排列,团块中央肿瘤细胞多由透明细胞组成,伴有均质性角化,部分瘤细胞有显著的异型性和核分裂象。诊断:外毛根鞘癌。给予一个疗程的放射治疗后,患者失访。
Female patient, 76 years old. Right temporal ulcer gradually increased 5 years, increased 2 months. Skin lesions showed a 7cm × 5cm right ulnar ulcer, clear boundary, embankment uplift, the surface accompanied by purulent discharge, a dark red after the right ear 2cm × 2cm mass. Histopathology showed that the epidermis was roughly normal, the dermis showed a large number of tumor cell clumps in the form of leaf-like distribution, not connected with the epidermis. The tumor cells at the edge of the clumps were arranged in a palisade pattern. The central tumor cells in the clumps were mostly composed of clear cells Composition, with homogeneous keratosis, part of the tumor cells were significant atypia and mitotic figures. Diagnosis: outer hair root sheath cancer. After giving a course of radiation therapy, the patient was lost.