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目的探讨脑钠素(BNP)对心衰诊断及心功能评估的价值。方法应用美国Triage诊断仪检测心衰组和健康组晨起空腹血BNP水平。结果心衰组BNP值明显高于对照组,差异有统计学意义(P<0.01),且心力衰竭组随NYHA分级增高其BNP水平越高。心功能Ⅰ~Ⅱ级与心功能Ⅲ、Ⅳ级比较,BNP水平差异有统计学意义(P<0.01)。结论BNP水平对心力衰竭的诊断及危险分层有较肯定的预测价值。
Objective To investigate the value of BNP in the diagnosis of heart failure and assessment of cardiac function. Methods The BNP level of fasting blood in heart failure patients and healthy volunteers were detected by Triage Diagnostic Instrument. Results The BNP level in heart failure group was significantly higher than that in control group (P <0.01), and the BNP level in heart failure group was higher with NYHA classification. There was significant difference in BNP levels between Ⅰ ~ Ⅱ level of cardiac function and Ⅲ, Ⅳ level of cardiac function (P <0.01). Conclusions BNP levels have a positive predictive value in the diagnosis and risk stratification of heart failure.