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慢性病毒性肝炎通常指病程超过6个月以上的肝脏炎症性疾病。一般由乙型肝炎病毒(HBV)和非甲非乙型病毒(NANB)所引起,甲型肝炎不发展成慢性。本文着重讨论慢性肝炎(CAH)的发病机理,其中免疫反应和结缔组织增生是决定该病发展的关键因素。一、免疫发病机理乙型病毒性肝炎的发病机理取决于病毒和人体免疫系统相互作用的结果。HBV本身并不直接损害肝细胞,因为健康的慢性HBsAg携带者,其肝细胞胞浆内有丰
Chronic viral hepatitis usually refers to the liver disease lasting more than 6 months. Hepatitis A virus (HBV) and non-A non-B virus (NANB) are generally caused by hepatitis A does not develop into chronic. This article focuses on the pathogenesis of chronic hepatitis (CAH), in which immune responses and connective tissue hyperplasia are the key determinants of the disease’s development. First, the immune pathogenesis The pathogenesis of hepatitis B virus depends on the interaction between the virus and the human immune system results. HBV itself does not directly damage the liver cells, because healthy chronic HBsAg carriers, the hepatocyte cytoplasm abundance