目的 :进一步了解氯氮平与其他抗精神病药物致白细胞减少的差异。方法 :按标准对收集的氯氮平与其他抗精神病药物致白细胞减少的对照研究论文作Meta分析。结果 :①氯氮平与其他抗精神病药物导致白细胞减少差异非常显著 (χ2 =7.2 5 7,P <0 .0 1) ;②氯氮平引起白细胞减少的机率是其他抗精神药物的 1.49倍。结论 :氯氮平与其他抗精神病药物导致白细胞减少差异非常显著 OBJECTIVE: To further understand the differences in leukopenia caused by clozapine and other antipsychotics. METHODS: Meta-analysis was performed on a standardized controlled-study paper of leukopenia of clozapine and other antipsychotics collected. Results: (1) The difference of leukopenia caused by clozapine and other antipsychotics was significant (χ2 = 7.25 7, P <0.01). ② Clozapine was 1.49 times more likely to cause leukopenia than other antipsychotics. Conclusion: The difference of leukopenia caused by clozapine and other antipsychotics is very significant