药物是治疗疾病的主要手段,严格掌握临床用药指征,避免滥施药物,是一个重要的问题。合理的药物治疗,能消除疾病的痛苦和增进患者的健康,滥用药物或使用不当,则可能使疗效降低、毒副作用增加甚或引起医源性疾病,给患者造成不应有的痛楚。在近代临床治疗中,多种药物联合使用似已形成“常规”,因而引起的各种药物在体内相互作用的副反应,已成为一个亟待研讨的课题。当多种药物不恰当地联合使用,在临床上产生明显不良反应,如低血糖休克、惊厥、出血等时,比较容易受到重视。但在另一种情况下,如美加明和尿路酸化剂合用,胍乙啶和麻 Drugs are the primary means of treating diseases. It is an important issue to strictly grasp the indications for clinical use and to avoid excessive abuse of drugs. Rational drug treatment, to eliminate the pain of the disease and improve patient health, abuse of drugs or improper use, it may reduce efficacy, increased side effects or even cause iatrogenic disease, causing undue pain to patients. In modern clinical treatment, the combination of multiple drugs seems to have formed a “conventional”, which caused side effects of various drugs interacting in the body, which has become an issue to be studied urgently. When a variety of drugs are not properly used in combination, clinically significant adverse reactions, such as hypoglycemia, convulsions, bleeding, etc., easier to be valued. But in another case, such as mecamylamine and urinary tract acidifier, guanethidine and hemp