论文部分内容阅读
众所周知应激刺激是引起抑郁症的重要病理因素,在药理学的研究中亦采用多种应激原造成动物的抑郁模型,而且抑郁症状本身也可提高病人对应激原有害作用的反应性。本研究主要观察、评价尼古丁对情感性障碍疾病的作用。采用三种小鼠应激模型(条件性恐怖刺激试验、悬尾试验和强迫游
It is well-known that stress stimulation is an important pathogenic factor that causes depression. In the study of pharmacology, a variety of stressors are used to induce depression in animals, and the depressive symptoms themselves can also improve the patient’s responsiveness to the harmful effects of stressors. This study mainly observed and evaluated the effect of nicotine on affective disorders. Three mouse stress models (conditional fearful stimulation test, tail-suspension test and forced swim) were used