论文部分内容阅读
中药“十八反”是在相反基础上形成的一组严格的配伍禁忌,然而从古至今临床应用反药治疗疾病的例子却层出不穷。反药是否相反,现代药性理论争议很多,并且也尚未形成较统一的判断标准和结论。通过查阅文献,从临床应用、制剂及给药方式、配伍比例、对P450酶系影响和毒理方面介绍了“十八反”中有关“海藻、大戟、甘遂、芫花反甘草”的研究现状,指出以往“藻戟遂芫俱战草”的研究,主要集中在急性毒性、长期毒性,对特定部位的实验研究还很少,并且存在药物基源、给药方式、配伍比例等实验条件不统一的现象,在此基础上提出应规范实验条件,降低各种不确定因素的影响,还应根据不同药物的作用特点从特定部位对海藻、大戟、甘遂、芫花配伍甘草进行系统研究,以期为藻戟遂芫伍甘草的准确用药和进一步深入研究提供文献基础。
Traditional Chinese medicine “eighteen anti” is formed on the contrary based on a set of strict compatibility taboo, but since ancient times the clinical application of anti-drug treatment of diseases are endless examples. Whether the anti-drug is the opposite, there are many controversies in the modern theory of medicinal properties, and a more unified standard of judgment and conclusion have not yet been formed. By referring to the literature, this paper introduces the related “seaweed, euphorbia, kansui, and Daphne genkwa antigens in” Eighteen Antibodies “from the aspects of clinical application, preparation and administration mode, compatibility ratio, influence on P450 enzyme system and toxicology Licorice ”research pointed out that in the past “ algae Sui Yuan war grass grass ”research, mainly focused on acute toxicity, long-term toxicity, experimental research on specific parts is still small, and the existence of drug-based sources, administration Methods, compatibility ratio and other experimental conditions are not uniform phenomenon, on this basis should be standardized experimental conditions to reduce the impact of various uncertainties, but also according to the characteristics of different drugs from specific parts of the seaweed, Euphorbia, Gan Sui , Daphne genkwa with licorice for systematic research, with a view to the accurate application of Phyllostachys coriander and licorice herbs and further study provide the basis for the literature.