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目的探讨采用无创呼吸机治疗慢性阻塞性肺疾病(COPD)合并呼吸衰竭的疗效。方法 60例慢性阻塞性肺疾病合并呼吸衰竭患者,随机分为观察组和对照组,每组30例。两组患者均给予抗感染、解痉平喘、保持水电解质平衡、纠正酸碱失调、化痰等常规治疗,观察组在常规治疗的基础上加用无创呼吸机治疗。观察两组治疗前及治疗后24 h、72 h的症状、动脉血气分析指标、住院时间及临床表现等。结果治疗后24、74 h观察组各动脉血气分析指标均明显优于对照组,差异均具有统计学意义(P<0.05);观察组平均住院时间为(23±3)d,短于对照组的(29±4)d,差异具有统计学意义(P<0.05)。结论无创呼吸机治疗慢性阻塞性肺疾病合并呼吸衰竭,可迅速纠正缺氧及二氧化碳潴留,疗效显著。
Objective To investigate the curative effect of non-invasive ventilator on chronic obstructive pulmonary disease (COPD) with respiratory failure. Methods Sixty patients with chronic obstructive pulmonary disease and respiratory failure were randomly divided into observation group and control group, 30 cases in each group. Both groups were given anti-infective, antispasmodic and anti-asthmatic, to maintain water and electrolyte balance, to correct the acid-base disorders, phlegm and other conventional treatment, the observation group on the basis of conventional treatment with non-invasive ventilator therapy. Two groups were observed before and 24 hours after treatment, symptoms of 72 h, arterial blood gas analysis, hospitalization time and clinical manifestations. Results The indexes of arterial blood gas analysis in observation group were significantly better than those in control group 24 and 74 h after treatment (all P <0.05), and the average length of stay in observation group was (23 ± 3) d, shorter than that of control group (29 ± 4) d, the difference was statistically significant (P <0.05). Conclusion Non-invasive ventilator for chronic obstructive pulmonary disease with respiratory failure can quickly correct hypoxia and carbon dioxide retention, with a significant effect.