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作为肿瘤标记物的种类虽多(如肝癌的AFP、消化道癌的CEA、肝胆胰的CA—19—9,α_1—AT等),但它们的化学成分却不外是糖蛋白或粘蛋白(含氨基已糖超过4％的糖蛋白),因此单一地测定某种肿瘤标记物阳性率不高,特异性不强并与某些良性病或健康人的假阳性交叉。基于上述观点,标记物既然是糖蛋白就不必考虑肿瘤的种类或它的标记物是什么。由于肿瘤细胞生物学的特性及其代谢特点,大多能反映
Although there are many types of tumor markers (such as AFP of liver cancer, CEA of digestive tract cancer, CA-19-9, α_1-AT of hepatobiliary and pancreatic cancer, etc.), their chemical composition is no more than glycoprotein or mucin ( Contains more than 4% of glycoproteins containing aminohexose. Therefore, the positive rate of a single tumor marker alone is not high, the specificity is not strong, and it crosses with some benign diseases or false positives in healthy people. Based on this point of view, since the marker is a glycoprotein, it is not necessary to consider the type of tumor or what its marker is. Due to the characteristics of tumor cell biology and its metabolic characteristics, most of them reflect