甲苯二异氰酸酯(toluene diisocyanate,TDI)是一种重要的化工原料,也是一种具有较高风险的环境污染物质,其接触人群众多,职业危害严重,已引起广泛的关注和研究。本文介绍了TDI的理化性质、毒性、职业接触限值、检测方法、生物标志物以及职业接触生物限值等研究现状,为保护职业接触人群的健康、研究制定生物接触阈限值提供参考。 Toluene diisocyanate (TDI) is an important chemical raw material and also a high risk environmental pollutant. It has attracted a great deal of population and serious occupational hazards and has drawn wide attention and research. In this paper, the physical and chemical properties of TDI, toxicity, occupational exposure limits, detection methods, biomarkers and biological contact limits of occupational exposure are introduced to provide references for the study of bio-contact threshold limits for the protection of occupational exposure to health.